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Dupuytren’s contracture is a type of hand deformity that causes the shortening and hardening of muscles, tendons, or other connective tissue. In this, the layer of tissue underneath the skin of the palms becomes knotted. This eventually creates a thick cord that pulls one or more fingers into a bent position.

The human body has several types of connective tissues, each performing a crucial function. Some tissue provide a medium to diffuse oxygen, nutrients, and waste, going back and forth from cells. Others provide the much-needed resistance to stretching forces such as muscles, tendons, and ligaments. Dupuytren’s contracture is a rare disorder that results in the thickening and tightening of elastic tissue, a form of connective tissue, right under the skin of the palm and fingers.

A hand deformity, Dupuytren’s contracture is a condition that affects the layer of the tissue situated under the skin of the palm. It forms tissue knots under the skin and slowly creates a thick cord that pulls one or more fingers in a crooked position. Typically, Dupuytren’s contracture is observed in the two fingers farthest from the thumb and tends to occur in men over 50 who are of Northern European descent.

Tenosynovial giant cell tumor – Diagnosis and Treatment Tenosynovial giant cell tumor (TGCT) belongs to a cluster of rare tumors which develop in the joints. In most cases, TGCT isn’t cancerous, however, it could end up damaging the surrounding joint structures. It affects three areas of the joint known as synovium, bursae, and tendon sheath.

As formidable as it sounds, the tenosynovial giant cell tumor is not malignant. But this group of rare tumors tends to develop in the joints, accompanied by their own set of problems. Although the tenosynovial giant cell tumor isn’t cancerous, it keeps growing and can damage the surrounding regions. These tumors tend to grow in three areas of the joint: